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AU680 Clinical Chemistry Analyzer

Fastest AU Analyzer Ever.

The The newest member of the high-performance Beckman Coulter laboratory analyzer series is the AU680 Chemistry System. Based on in-depth customer consultation, the AU680 Chemistry System is intended to help medium to high throughput laboratories meet ever increasing pressures on time and productivity.


The benefits of the AU680 Chemistry System can be divided into three main categories – improved user convenience including automation options; extended analytical reach and reduced operating costs. Regarding convenience, the AU680 Chemistry System is operated through a new and highly intuitive graphical user interface, including embedded videos to support key maintenance steps. Flexibility is assured with a menu capacity of up to 63 different assays on board. A new special priority lane performs re-runs quickly. To increase automation levels, samples can be loaded via a new standardized rack tray for direct transfer from the Beckman Coulter AutoMate 2500 peri-analytical workstation. 

Triple reagent dispensing enables the AU680 Chemistry System to perform assays requiring up to three separate reagents. This enhances analytical performance and opens up new possibilities for current and future assays. Overall, operating costs are reduced by eliminating the need for multiple calibrators via “Plug and Play” calibration using 2D barcodes.

Finally, the AU680 Chemistry System offers a speed of up to 1200 tests per hour and an on-board capacity of up to 63 different tests in parallel. Profit from innovative features and clear benefits for your lab!



AU680 Specifications


      Improved convenience

  • New and intuitive graphical user interface

  • Excellent overview and precise software guidance

  • Embedded maintenance video



    New analytical horizons

  • Handling of 3-shot reagents





    Plug and play calibration via 2D barcode

  • Minimized reagent volumes

  • Eliminates need for multiple calibrators

  • Applies to C3, C4, Transferrin and ASO



    Sample feeder

  • Positive sample identification to eliminate any sample mix ups

  • Beckman Coulter flexible racks to handle all commonly used tube sizes in parallel

  • Barcoded racks to define different sample materials or other sample specifics

  • 150 samples on board at any time for long walk away

  • Reflex testing

  • Priority re-run lane



    Refrigerated reagent compartments

  • Real workstation consolidation with up to 60 different analytes in parallel

  • Ready to use liquid stable reagents

  • Automatic bottle switch capabilities

  • Advanced calibration

  • Liquid detection and remaining test number calculation



    Washing station

  • High tech wash station to ensure a valid diagnostics

  • Two different detergents to prevent any carry over

  • Four fold water cleaning followed by a separate drying step to gain optimum system





  • High precision mixer station to ensure excellent reaction conditions

  • Standardized mixing procedures across the whole range of analyzers

  • Different mixer positions for individual reaction steps



    Cuvettes wheel

  • Non disposable quartz cuvettes

  • Software driven carry over elimination

  • Total reaction volume as small as 120 µl

  • Environmental friendly



    ISE unit

  • High quality ISE for Na, K and Cl

  • 6 months shelf life

  • 18 months shelf life for reference electrodes

  • 600 tests/hour (if ISE mode only)

  • Same technology across the whole range of analyzers




    Sample probe

  • Sample volume as small as 1.6 µl

  • Clot detection

  • Crash prevention

  • Sampling frequency of 4.5 seconds




    STAT sample rotor

  • Dedicated STAT rotor with 22 positions and integrated barcode reader

  • Full STAT capabilities during routine operation

  • Refrigerated area for calibrators and controls

  • Combined routine and emergency work area




    Reagent probes

  • Tact frequency 4.5 seconds

  • Reagent volume as small as 15 µl

  • Liquid detection

  • Calculation of remaining tests/vial





Analytical system

Fully automated, random-access chemistry system with STAT capability

Analytical principle

Spectrophotometry and potentiometry

Analytical types

Endpoint, rate, fixed point and indirect ISE

Analytical methods

Colorimetry, turbidimetry, latex agglutination, homogeneous EIA, indirect ISE

Simultaneously processed analytes

60 photometric tests + 3 ISE


800 photometric tests/hour; up to 1,200 with ISE

Sample types

Serum, urine, whole blood (HbA1c), other 1, other 2

Sample feeder

Racks with 10 samples each (bar codes on primary tubes and on racks); capacity of 150 samples; continuous loading

Sample tubes

In primary and secondary tubes; diameter between 11.5 and 16.5 mm; height between 55 and 102 mm

STAT samples

Up to 22 positions for STAT samples, bar-coded primary tubes

Sample volume

1–25 μL in 0.1 μL increments (1–25 μL for repeats)

Reagent supply

60 positions for R1, 48 positions for R2; (refrigerated 4–12 °C), handling of 3-shot reagents

Reagent volume

R1: 15–250 μL; R2: 15–250 μL; (in 1 μL increments)

Total reaction volume

120–425 μL

Reaction cuvette

Quartz cuvettes

Reaction time

Up to 8 minutes, 40 seconds

Reaction temperature

37 °C

Mixing method

With rotating paddles after dispensing sample and reagent

Photometry system

Direct assay through the reaction cuvette (0 – 3.0 OD) mono and bichromatic measurements possible


13 different wavelengths between 340 – 800 nm

Cuvette cleaning

Comprehensive cleaning with detergents


Autocalibration, cooled calibrator positions; master calibration established by two-dimensional bar code of the reagent bottle (>3-point calibration)

Quality control

Auto QC, cooled QC positions

Test requisition

Individual and profile test requisition via on line, mouse, functions keys or touch screen


Clot detection and crash prevention for sample and reagent dispenser


Full uni- and bidirectional communication possible


Windows XP®

Data Storage

Sample number 100,000 samples. Reaction Data 200,000 tests

Dimensions (W x H x D) mm

ANL 1,950 x 1,280 x 1,000

Power supply

200 V; 208 V; 220 V; 230 V; 240 V; 50 Hz; 60 Hz/3.8 KVA

by Beckman Coulter
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