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AU480 Clinical Chemistry Analyzer

Fastest AU Analyzer Ever.

With a throughput of 400 photometric tests per hour (up to 800 with electrolytes) and an on board capacity of 63 different analytes the AU480 Chemistry System is the ideal main analyzer for small to medium sized laboratories. The AU480 Chemistry System can also fit as a special chemistry or STAT analyzer in large laboratories as well.

TheAU480 Chemistry System maintains many features of its predecessor the AU400 that made it successful; long life electrodes, low maintenance and superior spot photometer technology.


More than 120 different Beckman Coulter System reagent applications are available including Serum Indices, specially designed to match the requirements and features of the new analyzer platform. The reagents are barcoded, in addition with 2-D master calibration curves.

Guaranteed standardization of results with the implementation of Universal applications "One Application fits all for all AU systems".

The system has twin sampling capability via rack loading or a cooled STAT turntable module. The sample rack feeder can hold up to 80 primary and secondary tubes in parallel.


Different tube sizes may be mixed within the racks and can be loaded continuously. The STAT module provides quick emergency testing, on-board calibrator and QC storage for system access during auto calibration and auto QC.

New state of the art sample and reagent volumes have been reached. Sample volumes as low as 1 µl, ideal for pediatric testing and reaction volumes down to as low as 90 µl guarantees cost efficiency. 
Computer controlled sample- and reagent dispensing based on CAN* technology in combination with clot detection and crash prevention are additional safety features which result in unique system reliability. The system security is further improved by context sensitive help screens and videos.

The AU480 Chemistry System has a new intuitive Graphic user interface, standardized to the AU680 minimizing any training requirements. A new ergonomically designed swing arm with a user friendly touch screen monitor is now available. User definable software options such as auto rerun via rack handler / STAT wheel and true reflex testing expand the convenience for the user.

Automated low level maintenance requiring minimum hands-on time by the operator. TheAU480 Chemistry System uses dry bath technology therefore requiring no water bath maintenance. Low consumable replacement for example permanent cuvettes, long life electrodes (guaranteed for 6 months), robust sample and reagent probes.

The AU480 Chemistry System combines versatile advanced functions that facilitate high quality testing, improve turnaround time and cut operating costs. To minimize training requirements and assure safe handling by inexperienced staff, we emphasized ‘Easy to Use’ in developing the analyzer. 

TheAU480 Chemistry System will continue to live up to the Beckman Coulter reputation of being the analyzer that is "reliable and precise".



AU480 Specifications


Improved convenience

  • New and intuitive graphical user interface

  • Embedded maintenance videos

  • Universal applications




  • Reagent reduction

  • Low consumable usage

  • Microsampling ideal for pediatrics



Continuous loading sample feeder

  • Positive sample identification

  • Beckman Coulter flexible racks to handle all commonly used tube sizes in parallel

  • Barcoded racks to define different sample materials

  • 80 samples on board at any time

  • Automatic repeat and reflex capability



Flexible STAT rotor

  • Dedicated STAT rotor with 22 positions and integrated barcode reader

  • Full STAT capabilities during routine operation

  • Refrigerated area for calibrators and controls



Large reagent compartment

  • 76 refrigerated reagent compartments

  • Ready to use liquid stable reagents

  • Automatic bottle switch capabilities

  • Advanced calibration



Cuvette wheel with low maintenance

  • Non disposable quartz cuvettes

  • Software driven carry over elimination

  • Dry incubation bath



Best in class ISE

  • High quality ISE for Na, K and Cl

  • 6 months shelf life

  • 18 months shelf life for reference electrodes

  • 600 tests/hour (if ISE mode only)

  • Same technology across the whole range of analyzers




Analytical system

Fully automated, random access chemistry system with STAT capability

Analytical principle

Spectrophotometry and potentiometry

Analytical types

Endpoint, rate, fixed point and indirect ISE

Analytical methods

Colorimetry, turbidimetry, latex agglutination, homogeneous EIA, indirect ISE

Simultaneously processed analytes

60 photometric tests + 3 ISE, 120 pre-programmed onboard tests


400 photometric tests/hour; maximum of 800 with ISE

ISE throughput

200 samples/hr.Maximum test/hr 600 if ISE only

Sample types

Serum, plasma, urine, other

Sample feeder

Racks with 10 samples each (barcodes on primary tubes and on racks); capacity of 80 samples; continuous loading

Sample tubes

Primary and secondary tubes; diameter from 11.5 to 16 mm; height from 55 to 102 mm, nestled micro sample cups

STAT samples

Up to 22 positions for STAT samples via cooled turntable. Easy to operate interrupts between tests Auto repeat run capability

Sample volume

1–25 μl in 0.1 μl steps (1–25 μl for repeats)

Reagent capacity

76 positions for (R1+R2, detergent position). Holds 15, 30 and 60ml bottles

Reagent storage

Refrigerated (4 °C–12 °C

Reagent volume

R1: 10–250 μl; R2: 10–250 μl; (in 1 μl increment)

Total reaction volume

90–350 μl

Reaction cuvette

Permanent glass cuvettes

Reaction time

Up to 8 minutes, 37.5 seconds

Reaction incubation

37 °C, dry bath

Photometry system

Direct assay through the reaction cuvette (0 – 3.0 OD) mono and bichromatic measurements possible


13 different wavelengths between 340 – 800 nm


Auto calibration, cooled calibrator positions; master calibration established by two-dimensional barcode

Quality control

Auto QC, cooled QC positions


1. Auto rerun and manual rerun available
2. Automatic sample increase, decrease or normal repeat
3. Reflex testing

Sample Pre Dilution

Dilution ratio: Fixed to 3, 5, 10, 15, 20, 25, 50, 76 or 100

Test requisition

Individual and profile test requisition via on-line, mouse, function keys and touch screen

Sample integrity

Lipaemia, Haemolysis and Icterus analysis. Sample clot detection and probe crash protection


RS232C. Full uni- and bidirectional communication possible


Windows XP®

Data Storage

Sample number 100,000 samples. Reaction Data 200,000 tests

Dimensions (W x H x D) mm

ANL: 1,450 x 1,205 x 760

Power supply

100–240v; 60 Hz/ < 3.5 kVA

by Beckman Coulter
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